Adverse events are unwelcome occurrences that are associated with a medical intervention (e.g., drug, procedure). They may or may not be directly caused by the medical intervention—they can be caused by interactions with other drugs or other patient factors—and can vary in severity.
Adverse events are always important to monitor in research studies, but perhaps are especially important in ME/CFS. Many patients experiment with multiple treatments at a time, which can increase the likelihood of experiencing an adverse event. There are also numerous symptoms to monitor over time, and sorting out whether they are a component of the disease or a reaction to a medical intervention can be challenging.
OMF’s first clinical trial, the Life Improvement Trial, includes periodic monitoring for adverse events. Read more about the trial in the protocol paper.
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